Philip Rivers threw his third interception of the game in the final seconds as the Raiders held off the Chargers 26-24 on Thursday Night Football in Oakland.
Raiders safety Erik Harris had two interceptions, including a 56-yard pick-six in the first quarter to give Oakland an early lead.
Rookie Josh Jacobs ran 18 yards for the go-ahead TD with 1:02 to play to put the now 5-and-4 Raiders up for good.
Rivers passed for 207 yards and two TD's, but also took five sacks for the Chargers.
Melvin Gordon rushed for 108 yards and a score for LA, which dropped to 4-and-6.